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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63992d67d2ec9681cb48b0d55a2f5bb90b8e5871e33913585f6e3e0bc1f5de81' 
  AND token = '4xeTBepM5aNkMaimUQK5RjLFn6uf5b9zz8ym13jUKcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}