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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8602c7ea1c43311c4946a8cc4e98798f6e55935c1aebbe87c090d9ae16f55e49' 
  AND token = 'NjDmlNXz78kc2v40S/CjqtCbPWngDF9PDpEGq6N9hgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}