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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f19b2d3a9f604b920168173fb6b01227d27a4e482a4c1d54581e429eaa84fe1' 
  AND token = '+GWIlP+fxFvsJ1e9/2Yp1W5j9q0KiSMXF59GXG1yyuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}