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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d1b0c2be011a9bc8cac146765bafb90425b70da4ca7113c1c4109ebec93fbab' 
  AND token = 'gqYEGNkrlhoH/PtItmEjp+LLc5YrKcg3y/MyVU6l1jM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}