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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e81e33cd6e78932dd613d43b7dd0531fcaaaf7b8594c9128ff3266a4a7103fe2' 
  AND token = 'MFt0tpxetdtkPXxrK6RzDX1/iHdncaMaDs/rsnzWuWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}