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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c3acde87cf7f64937d3ef66b36797337aa9c415a84d0e004897b9d47853599d' 
  AND token = 'LwP2JypnnJ8i/i7stnWl+EcFS/2HXs/11YVW/XN5jbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}