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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24e5dd2911afe211339369db2934a21273f1df1c33c79953d463ed5d6387a3e2' 
  AND token = 'P1U1MJpX6utaTobJ05cWUycrJ/b1uyqdj7zj/pPb+Z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}