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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b3c3733650efddbc31a6cd57a12a62f2161a7435061dba91b6d23a6bdd5d96e' 
  AND token = 'O+lX/o5DSqRxOO5MiVW4sGMBwiVYruRoy/7ZV0jXAzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}