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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d6e43231658cf80e2aaf5977c69da9ee388fa830fab79fb80564a42fc9daeb8' 
  AND token = 'N8sIdCF2GeCHzumArjQ9P+Ac24Codgy8GCWA2D9TFMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}