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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21777f4d395e4c6f9190d13925d59e23fb46913ad5ea193b8ab101a52f378054' 
  AND token = 'XzBnnMJCNJiZOWyWTmXSaA95XA8I7WrZhHVd1Hv2opM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}