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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59a933de343c76b503b412759cef31d4aea557ded8c6198b752f56f8b4da3275' 
  AND token = 'P5buTMrQl1eSQYy9e+h7NXbtDS7idZeKWjiXZe6Z3og=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}