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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9658b86e90b6d7d91fa007ef424606e813da98dfed4dd121c1e08edbbe45c465' 
  AND token = 'ksa+ECmSxwtlep6GHVrgUbJJnLH0sT+L8YSZRzgoch4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}