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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '749ad312014f0762d9dcb0789c11b8a0b064520c60c156357bb0758fbac8eb08' 
  AND token = 'YLSoRJJ63h00UtRtVB1k4QRFfiQ8HNZkswXeaEbRdRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}