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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce57a886abf117f69fdee85b57d9a6c4ae45d593c446b7cd3b843bd1cac047a6' 
  AND token = 'xQXy9bqt33r84EBhB0nhxY+Zp9Ylsn4pXFBnlg+jAQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}