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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a422326f83cd74bde2fcb4a41895726407c1288e3bc5ac4fcf37366c516c5ca' 
  AND token = 'u0e8KlrVwNjcss5rIbNSVOgjyymXiuoJoYfX43BruYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}