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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7427b7bdc17da1edf9a41b803ef06e895305acf3a2bc2ada5fe530b2ae05d8c7' 
  AND token = 'L/JLUoqZGLyiW9e6kaL+WaLYDTiM4znUfujQMJbkmSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}