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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2426c5cb917f58e8e3f2b3e98e2833d78702a664b1db6f74762aa6dd1a0ba5cb' 
  AND token = 'CHLfVkQd42o3SnYLRdQ5Hf0aoQc7OUkYctdBnTQSYyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}