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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7443f7016e20913002c8196141540550a965e4438db1f6c77d420ca802e49ba' 
  AND token = '/S2T5bkihmgKZAtXm6vij0tcI+ekvkb8afjlwbWou4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}