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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3f6602a19a21cbccc34e0491b1da4e84b21c7c6fbd10564f27c4c19b0639e80' 
  AND token = 'eXoP9OTheAfQ4a+N0EDNf0DN5r7AtA7HrUy6gwgBuD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}