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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7290e9be277d1e2655b2bb9e80a07e4541dc9dcbdbc4e7b25d489db7158ad221' 
  AND token = '0KLSbYI/3dvWrb+5at66/rs3CxHikllV3D27UF+P9z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}