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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61847925376fe39a54dd019020a2bc1d5311f76b6f1727cc1237fcee7bb61b8f' 
  AND token = 'bPdhq/rAM+3Hh+g8Pn/XmpfUSY30bisCZHcXWJWReNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}