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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34b81a8df0a3012392ba6a4d5d019b4bb13100c915bdf62e73a22d5204217838' 
  AND token = '4fIFj5o8zi7iB+S7KAT93wJyBtuZbz6DsL2SxRRp4nA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}