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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e98cfd8a35591292cea963080d620826f85375cc2d8db6b117f7e16357bee1f6' 
  AND token = 'ZoB0v2hrn/uUlb9toagU+l56GIlSrc6Yw5iGSyrA/r8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}