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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60be48d9fcf139a8f9fa3ded9d842b87fbe3c32896340306f2f5fb6963c3f814' 
  AND token = 'CxS1/XAi7UgCYraK8ky27vVRdBk117fG98u03f2XERA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}