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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '036ff5d11c2b9c3f980c256e6720f1e15ebd78d6277cb554fce9ab6da78d1718' 
  AND token = 'IKSIo/z3iKHHH6dU01LUjbrWXnbleCFG4wmvGIP8Bz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}