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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d4514a49795a85ef3d4249d55310dd2f941ed64bf1d0bfbea7e2329d1839223' 
  AND token = '+nUX0ZP2aXdCRJV0AmsraR7Gg9K0giPJDJMLz3ciF8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}