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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3190918ffbdd6abb3d6c39b9f7a9c6dc6521106eee60f3972934c6ac238f2246' 
  AND token = 'YJbH6BCXP9JZ9/1QoWCQXvCle0OuIxkeVE4FvmiqLMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}