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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7ada3ece0ff32a2a39b0da7926b0e3b8dd7b59d5a011c8b9415926b908f584f' 
  AND token = 'l49t86B7dAXkbjWLOFAxaDUWpkOfGpx/hgQEi1zlZsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}