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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed0f97b6e1719decba8736cc32eff9f3cb63488ca6b3ebb4d26f8617557f8e40' 
  AND token = 'V7Z7dT1JUVOUz7Tzo2cJxwP9bPViRS7cvF+mnHU7Ko0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}