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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17778e357f5c00cb60f0bd2c8cc3304c17d6c9c468baca6977738335270cca24' 
  AND token = 'ZxOD2uiuUQyN9zUJNW+iEL7CwPVx7xqkUbXKZNfUNh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}