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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41ee5b64a7e413cb2871ade5cbc8d80795a0afb1c4ce52a021eac597d17b339b' 
  AND token = 'I+UBS/CuBWDFXjLWBHZgRkZFejPe+R2yKt/ftsMimLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}