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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c1a46e325cd46ba1fd279418ee21028553c67c0e2c4853ef52188e7fdb18c16' 
  AND token = 'v2gX3Nsioy0psnywwp4Vqe1B1xe51he0h0IPhYHMm+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}