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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf222ee1a9ea0d3e77ce3bb1f66c5ff4fd318683c9698e0f9a31f032a9ee4425' 
  AND token = 'ulFZBX9FMzLg8oL5rqVwlmEQYcaSYkeuELrIGoCka3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}