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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b6f143f102ecc68174fc582b1dc70d094e696eeb5038ebe57619a18db1a7c45' 
  AND token = 'J6+W9Tu9nIq7K9pF5UPaDM6NXRp7DBBzpXge2/3sN3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}