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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71a22f9453c5d2922d20f91d1b6214ace1e5711aeaf8698fe1cde3d121c8fb4a' 
  AND token = 'TSniQZaY55PMmGM2lqL5zCMPTl+QqGDLJ3d6yQC8dVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}