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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '979444c9820dc41b5076cc573281c13f6f3365c0d404165eba9581844b1b63ad' 
  AND token = '65i2UfeGW0x9qryIcCWuKPbM5da2Y9bXpUZb3QZGrgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}