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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccf6dc1d2c27aaa76b83a898994d3b06458eab3f563daa9c1cfdf39389b2cce7' 
  AND token = 'ixR2tti+Jmq35wdDanSkhbPgX/0+NtcnkOSbW++KYFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}