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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e50cd9ae5b5c1c43b0f71b7bfd5adcb306c9539e031a9c300997c105ac0e2acd' 
  AND token = 'hCy4M4i4V6ZU32noQ3QGt0n1jC+w62+l2MtGmYyw15M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}