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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '785b47ed3a2b5daf69f1cc882dffa08f6d74503382e1a0f0ddf46d0576e57b00' 
  AND token = '7H//fku2LDr4IQ13Gk8PaDzwIvmvh5njuNU5SoLWSjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}