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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '772a8fbb3f206eae12d8f900c18f6e503b6c2db6b41f506da346ae701faf5b24' 
  AND token = 'SuiPHgxKav014wh/n5IgPyYsYnMiBLSQkiq0GflOjW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}