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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e21c3148244518c20a7ddc1d9a2b18079e9e5f75dec6a8f9205674dee67318f' 
  AND token = '2/pk70jWtcwnK1aHT5gRGqb8KSQCvolQR4jiojSQUzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}