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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '267c0d411649b2623d4333cd0aa1eadca9f427c0d8b460c637157c23b6025148' 
  AND token = 'GSo+8qNc498hLkR4Uq93Ju2w0GZatcczJ6OMAl+xg8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}