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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e4f51207ccb4a4ce0fea53e009bb45a0578879e29c72e66e5bede331e5ff619' 
  AND token = 'AdVT+5aDg96ZKMSgTPF0Bij9XFz2reSQZZifA8Qmz4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}