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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc7acd88b365ce2f7314a31e476dce2110e62eba8bccd1e3b226cabf314e206b' 
  AND token = 'w0lYSz9BSW5SCk7NpINM/6P/OcTonZAr0JWrNz8mO4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}