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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '899c5a001b4a312f37f453d31a345d1ec6d06286c781debde41d1f7e8eb2a025' 
  AND token = '5twc+u050tqpXqTFlVhq6p/MYaxYH/gCE2IkDRQ3Ho4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}