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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9327a18079758182501f631085d774d365ec132cf8b68e24b73c3776bf74d2fe' 
  AND token = 'bGn+xv0UaSJHOsitBa0IvWjhxeNGuIxzkBGTnklh1Uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}