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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a71750de69a26c481f0b19cc06ad1b15579e978730b5105b5cf751140b2e569' 
  AND token = 'MIE3F4e/RpI/uLbXOLKupF0FM/ez6r2RfNDrIZhWuWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}