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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5be1f113764889780f500631002c410de4fbb6131f78099179f34b00f8324ac' 
  AND token = 'h1VecUk/YFh1TIc55pgHB3tVypjmFNMV2RSiWOvTzIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}