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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95aedc7781b6e4c67c52aab9e42186302b3c20d5d76b91a866918d5150c4e25c' 
  AND token = 'MZWi4PpPb/IsMKGmDZb/JSWyYx2MMERaRHkq+OuRY1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}