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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3797b2bc4ba6186f1c16fd315172fbcecb968696f2df9561a5aad5bac6c4ccb8' 
  AND token = 'XxbuMhQ+OFwRhdvYVukC5EVOLNNMXM+RLYuhebq2ZSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}